TOFMOD Workshop 2020 (satellite event of Virtual Physiological Human conference 2020) Speaker: Jorge Aramburu, TECNUN-Universidad de Navarra, Spain Title: Identifying parameters in 1-D/0-D modeling approach to model Fontan circulation Numerical models of the Fontan circulation can be used for virtually studying the response of the different actions taken by physicians. The correct balance between simplicity and accuracy of the model is of paramount importance. In this work we use reduced-order one-dimensional (1D) and zero-dimensional (0D) forms of the governing equations of haemodynamics and a 0D heart to model a patient-specific Fontan circulation. Model parameters are estimated based on pressure and flow measurements taken at various locations across the cardiovascular system using, respectively, cardiac catheterization and cardiovascular magnetic resonance imaging (CMR). A stepwise approach is taken to estimate the model parameteres: Step 1: Model parameters for the 1D aorta. Step 2: Model parameters for the 1D total cavopulmonary connection (TCPC). Step 3: Model parameters for the upper body and lower body 0D organs. Step 4: Model parameters for the 0D univentricular heart. Our results show that the model is able to reproduce the measured flow and pressure waveforms to a great extent. In estimating the model parameters, it is very important the proper time alignment of all the measured waveforms (flows, pressures, ventricle volume...), so that the results of the parameter estimation algorithm give useful results.